Title : Examination of the genome - wide transcriptional response of Escherichia coli 1 O 157 : H 7 to cinnamaldehyde exposure 2 3 Running Title : Transcriptional response of E . coli to cinnamaldehyde 4 5 6 7

Title: Examination of the genome-wide transcriptional response of Escherichia coli 1 O157:H7 to cinnamaldehyde exposure 2 3 Running Title: Transcriptional response of E. coli to cinnamaldehyde 4 5 6 7 Jeyachchandran Visvalingam, Juan David Hernandez-Doria and Richard A Holley* 8 9 10 Department of Food Science, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, 11 Canada 12 Department of Animal Science, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, 13 Canada 14 15 16 17 18 Current Address: The University of Texas Southwestern Medical Center, Dallas, TX, US 19 20 *Corresponding author: R.A. Holley, Tel: +1 (204)474-9601; Fax: +1 (204) 474-7630; E21 mail: [email protected] 22 23 Copyright © 2012, American Society for Microbiology. All Rights Reserved. Appl. Environ. Microbiol. doi:10.1128/AEM.02767-12 AEM Accepts, published online ahead of print on 26 November 2012